Densha de Go! Professional-shiyou 2 (loosely translated to "Go by Train! Professional Specification 2") is an electric train driving simulation game developed and published by Taito for the PlayStation 2 in Japan on October 25, 2002. It was later ported to the PC by Unbalance on April 30, 2003.

The sequel to the 1999 home console entry in the Densha De Go! series, Densha de Go! Professional-shiyou, Professional-shiyou 2 features a graphical upgrade and a new set of real-life train routes: the Shōnan-Shinjuku Line, the Tsurumi Line, the Kosei Line, the Seto-Ōhashi Line, and the Nagasaki Main Line to Sasebo Line. One new feature added to the series is the ability to save and resume route progress, and to start progress from a designated station.